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Transdermal Delivery Patch

Non-invasive, sustained-release formulations delivering drugs directly to systemic circulation — bypassing oral inefficiencies entirely.

Transdermal Delivery

Advanced Patch Technology

Transdermal Drug Delivery Systems (TDDS) are self-contained, discrete dosage forms. When applied to intact skin, they deliver drugs at a controlled rate directly to the systemic circulation — bypassing the hostile environment of oral administration entirely.

Unlike topical formulations which treat the skin itself, TDDS uses the skin merely as a portal to the bloodstream. By engineering formulations that navigate the Stratum Corneum and utilise the Dermal blood supply, Hoshi MedTech achieves systemic therapy without the invasiveness of needles or the variability of digestion.

Our patch technology represents a convergence of polymer science, pharmacokinetics, and patient-centric design — resulting in treatments that are not only clinically superior but genuinely easier for patients to integrate into daily life.

Transdermal patch application Pharmaceutical laboratory

Key Advantages

Avoids First-Pass Effect

Bypasses liver metabolism entirely for maximum drug bioavailability and consistent systemic dosing.

Steady Plasma Levels

Provides consistent plasma concentration — ideal for drugs with narrow therapeutic windows.

Non-Invasive & Pain-Free

Eliminates injections and GI exposure — dramatically improved patient experience and compliance.

Easy Termination

Therapy can be immediately stopped by removing the patch — unmatched clinical flexibility.

Product Portfolio

  • Lidocaine 5% Patch
  • Diclofenac Patch
  • Capsicum + Menthol Patch
  • Cooling Patch

Interested in this product?

Speak with our team about how this technology can enhance your therapeutic offerings.

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Pharmacology · Drug Delivery

Systemic Delivery vs Topical Advantages

Definition: Transdermal Drug Delivery Systems (TDDS) are self-contained, discrete dosage forms. When applied to intact skin, they deliver drugs at a controlled rate directly to the systemic circulation.

Key Distinction: Unlike topical formulations which treat the skin itself, TDDS uses the skin merely as a portal to the bloodstream.

Why it matters: Understanding the difference between topical and transdermal delivery is critical in clinical pharmacology — one stays local, the other achieves systemic therapeutic concentrations throughout the body.

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Topical Application

Local tissue effect

EPIDERMIS DERMIS HYPODERMIS BLOODSTREAM STAYS LOCAL ✕
Local Action
  • Drug disperses across skin surface and upper layers
  • Primary target is the epidermis and dermis tissue
  • Minimal systemic absorption is typical
  • Used for dermatological conditions (eczema, psoriasis)
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Transdermal Delivery

Systemic bloodstream entry

EPIDERMIS DERMIS HYPODERMIS BLOODSTREAM TDDS PATCH REACHES BLOOD ✓
Systemic Action
  • Drug penetrates all skin layers to reach bloodstream
  • Controlled release rate via patch membrane
  • Bypasses first-pass hepatic metabolism
  • Used for hormones, analgesics, nicotine replacement
Hoshi MedTech · TDDS Technology

The Completed Journey

TDDS PATCH EPIDERMIS DERMIS HYPODERMIS

Chemistry meets Biology —
precisely engineered

TDDS represents a precise balance of chemistry and biology. By engineering formulations that can navigate the Stratum Corneum and utilize the Dermal blood supply, we achieve systemic therapy without the invasiveness of needles or the variability of digestion.

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Stratum Corneum
Engineered formulations navigate the skin's primary barrier layer
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Dermal Blood Supply
Drug particles absorbed directly into the dermal capillary network
Systemic Delivery
Reaches systemic circulation — no needles, no GI variability